Online Event

7 May 2021

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Hours
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PRESENTATION

The past two years have seen an exponential increase of lay and scientific
publications on the effects of the trillions small guests that each of us more or less
willingly hosts  in the most secluded and intimate folds and holes of our body.
High time, given that the power house of eukaryotic cells, mitochondria, are but
ancient bacteria.
Reports have been published on the association of some bacterial strains in the guts
(gut bacteria being by far the most represented microbial community) on human
physiology (infant growth….) and somatic diseases (obesity, alcoholism, irritablebowel
syndrome and rheumatoid arthritis) and brain diseases (depression, autism,
multiple sclerosis, Parkinson’s disease, Alzheimer’s disease).
Reports have multiplied of animal experiments showing that some natural features
(resistance to infections and carcinogenic exposures) can be transferred from one
animal to another by gut bacteria transfer. Not only, but it is increasingly clear that a
number of environmental events can affect the bacterial composition of gut flora
(diet, physical exercise, exposure to cold), that the animals with the modified version
of the gut flora acquire specific physical and behavioral features (weight changes,
sociability, motor impairments), and that such features can be transferred to nonexposed
animals by gut bacteria transfer.
How much of these results is journalism hype and how much is sound science? How
close (or how far for that matter) are we from gut flora manipulations in humans to
protect from dreaded brain diseases?
The 4rt edition of this conference, which previously attracted 500 participants from
Europe, will try and give an answer thanks to a panel of renowned national and
international experts on the microbiota and the brain.

AIMS

To update physicians and scientists on the latest discoveries on the role of the GMB
in neuropsychiatric and neurodegenerative diseases.
To identify leads for microbiota-based interventions for brain diseases.

PUBLIC

Physicians, neuroscientists, biologists.

PRESENTATION FORMAT

Fully online, Registered videoconference

Program

8.00

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8.00

Welcome Address

Giovanni B. Frisoni

Faculty of Medicine & University Hospitals of Geneva

8.15

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8.15

Neurodegenerative diseases and microbiota

A. Cattaneo

moderator

8.15

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8.15

Understanding relationships between the microbiome and cognition: opportunities for cognitive enhancement

Con Stough

8.30

white

8.30

Potential Role of Gut Microbiota in ALS Pathogenesis and Possible Novel Therapeutic Strategies

Letizia Mazzini

8.45

8.45

Gut microbiome composition and function in persons with Parkinson's disease

white

Rejko Kruger

9.00

9.00

Gut microorganisms act together to exacerbate inflammation in spinal cords

white

Hiroshi Ohno

9.15

9.15

Q & A

white

9.35

9.35

Main Lecture: personalised medicine and microbiota

white

J. Schrenzel

moderator

9.35

9.35

Host Micro Biome Interactions In Health And Disease

white

Eran Elinav

10.05

10.05

Q & A

white

10.15

10.15

break

white

10.25

10.25

Technological breakthrough

white

J. Schrenzel

moderator

10.30

10.30

An innovative organ-on-a-chip platform to study the microbiota–gut–brain axis in neurodegeneration

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Carmen Giordano

10.30

10.30

Engineered phages as personalised precision antimicrobials

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Samuel Kilcher

11.00

11.00

Q & A

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end of morning session

white

16.30

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16.30

Main Lecture: Microbiota and neurodevelopment

m. Marizzoni

moderator

16.30

16.30

The maternal microbiome modulates fetal neurodevelopment in mice

white

Helen Vuong

17.00

17.00

Q & A

white

17.10

white

17.10

Insight of brain diseases/microbiota mechanistic interaction with animal model and clinical studies

Giovanni B. Frisoni

moderator

17.10

17.10

Pathways underlying the transfer of autistic behaviour from humans to mice

white

Sarkis k. Mazmanian

17.40

17.40

The gut microbiota modulates central and peripheral innate immunity in Alzheimer’s disease

white

Laura Cox

17.55

17.55

The bidirectional link between CNS and gut microbiota in epilepsy and other neuropsychiatric diseases

white

Pasquale Striano

18.10

18.10

Microbiota transfer therapy as potential treatment for children with autism spectrum disorder

white

Rosa Krajmalnik-Brown

18.40

18.40

Q & A

white

19.10

white

19.10

Conclusion

Giovanni B. Frisoni

Organisers

Giovanni B. Frisoni

Faculty of Medicine & University Hospitals of Geneva

J. Schrenzel

Faculty of Medicine & University Hospitals of Geneva

A. Cattaneo

Faculty of Medicine & University Hospitals of Geneva

Scientific Board

Moira Marizzoni, Claire Chevalier, Benjamin Tournier

POST GRAD CME

E credits will be requested to: Association des médecins du canton de Genève, FAMH Medical Laboratories of Switzerland, Swiss Neurological Society, Swiss Professional Society of Geriatrics, Swiss Society of Gastroenterology, Swiss Society of General Internal Medicine, Swiss Society of Psychiatry and Psychotherapy and Association Suisse des Neuropsychologues.

Registration

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